A4813
Fluka
3-(N-Acetylamino)-5-(N-decyl-N-methylamino)benzyl alcohol
| Synonym: | ADMB |
| CAS Number: | 103955-90-4 |
| Linear Formula: | C20H34N2O2 |
| Molecular Weight: | 334.50 |
| MDL number: | MFCD00132953 |
| PubChem Substance ID: | 24890915 |
Description
| Biochem/physiol Actions | A designed activator of protein kinase C shown to increase the surface expression of the tumor-associated antigen BCA 225 and various cellular antigens in T47D cells. |
Properties
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| WGK Germany | 3 |
References
| reference | Wender P. A., Analysis of the phorbol ester pharmacophore on protein kinase a guide to the rational design of new classes of analogs. Proc. Natl. Acad. Sci. U. S. A. 83, 4214, (1986) |
| Leon, J. A., Modulation of the antigenic phenotype of human breast carcinoma cells by modifiers of protein kinase C activity and recombinant human interferons. Cancer Immunol. Immunother. 35, 315, (1992) |
